William Frazier may refer to:
- Wayne Frazier (William Wayne "Cotton" Frazier Sr., 1939–2012), American football player
- William Frazier (Wisconsin politician) (1833–1902), Wisconsin state legislator
- William Frazier (Virginia politician) (1812–1885), Virginia state legislator
- William H. Frazier (1838–?), state legislator in South Carolina
This disambiguation page lists articles about people with the same name.
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