Wikipedia:WikiProject U.S. Roads/Pennsylvania/Selected article/August 2010

Pennsylvania Route 666 is an east–west state route located in northwest Pennsylvania. The western terminus of the route is at U.S. Route 62 in the Hickory Township municipality of East Hickory, and its eastern terminus is at U.S. Route 6 in the hamlet of Sheffield in the township of the same name. It cuts through most of Allegheny National Forest, and is therefore sparsely populated, with the largest settlement along the road being Endeavor, Pennsylvania. Its official name is the David Zeisberger Memorial Highway.

The route was assigned in the 1928 numbering of State Routes in Pennsylvania. The highway originally ended in Nebraska, Pennsylvania until being extended southward along other streets. The route was realigned in 1946 onto its present routing. The highway has remained the same since.