Wikipedia:Reference desk/Archives/Science/2023 April 12

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April 12

Does Humulus lupulus leaf contain estrogen?

Is the estrogen of Hops in the leaf or in another part/s of the plant?

Thanks, 2A10:8012:19:AD67:9807:EAF6:E6B1:5A7B (talk) 21:38, 12 April 2023 (UTC)

Yes, and in strobili ("cones", i.e. hops). --136.56.52.157 (talk) 23:28, 12 April 2023 (UTC)

To clarify, hops are from the "cone" part of the plant (Humulus lupulus); and for example, the leaves of the plant itself are not used for making beer. The leaf-like structures of the strobili are referred to as decussation; which, if I understand correctly, relates to their being a "cross" between a stem and a leaf. All parts of the plant (AFAICT) contain 8-Prenylnaringenin, considered to be the most potent plant estrogen (estrogenic phytoestrogen). --136.56.52.157 (talk) 03:26, 13 April 2023 (UTC)

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Sources

• Milligan, S. R.; Kalita, J. C.; Heyerick, A.; Rong, H.; De Cooman, L.; De Keukeleire, D. (1 June 1999). "Identification of a Potent Phytoestrogen in Hops (Humulus lupulus L.) and Beer". The Journal of Clinical Endocrinology & Metabolism. 84 (6): 2249–2249. doi:10.1210/jcem.84.6.5887.
• Chadwick, L.R.; Pauli, G.F.; Farnsworth, N.R. (January 2006). "The pharmacognosy of Humulus lupulus L. (hops) with an emphasis on estrogenic properties". Phytomedicine. 13 (1–2): 119–131. doi:10.1016/j.phymed.2004.07.006.

P.s.: I thoroughly messed up inline citations; two sources are above --136.56.52.157 (talk) 03:44, 13 April 2023 (UTC)