Weyanoke may refer to:
- Weyanoke people, historic American Indians who lived on the Weyanoke Peninsula in Virginia in the 17th century, which English colonists named after them
- Weyanoke, Louisiana, an unincorporated community
- Weyanoke, Virginia, an unincorporated community
- Weyanoke, West Virginia, an unincorporated community
This disambiguation page lists articles associated with the title Weyanoke.
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