WGBS may refer to:


  • WGBS-LD, a low-power television station (channel 11) licensed to serve Hampton, Virginia, United States
  • WAQI, a radio station (710 AM) licensed to serve Miami, Florida, United States, which used the call sign WGBS until October 1985
  • WINS (AM), a radio station (1010 AM) licensed to serve New York, New York, United States, which formerly used the call sign WGBS
  • WLTV, a television station (channel 23 analog/24 digital) licensed to serve Miami, Florida, which used the call sign WGBS-TV from 1956 to 1968
  • WPSG, a television station (channel 57 analog/32 digital) licensed to serve Philadelphia, Pennsylvania, United States, which used the call sign WGBS-TV from October 1985 to December 1995
  • WGBS, a fictional television station depicted in DC Comics publications
  • Watford Grammar School for Boys, in Watford, Hertfordshire, United Kingdom
  • Whole genome bisulfite sequencing, a NGS technology to determine DNA methylation