VPS26B

Vacuolar protein sorting 26 homolog B (S. pombe) is a protein in humans that is encoded by the VPS26B gene.

VPS26B
Identifiers
Aliases	VPS26B, Pep8b, VPS26 retromer complex component B, VPS26, retromer complex component B
External IDs	OMIM: 610027; MGI: 1917656; HomoloGene: 3601; GeneCards: VPS26B; OMA:VPS26B - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q25 Start 134,224,671 bp End 134,247,788 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 A4 Start 26,919,067 bp End 26,941,361 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum skin of arm ganglionic eminence granulocyte right frontal lobe prefrontal cortex skin of leg Brodmann area 9 skin of abdomen cingulate gyrus Top expressed in ascending aorta aortic valve granulocyte Region I of hippocampus proper subiculum nucleus accumbens supraoptic nucleus cerebellar cortex barrel cortex olfactory tubercle More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm retromer complex late endosome early endosome membrane retromer, cargo-selective complex endosome cytosol phagocytic vesicle Biological process protein transport retrograde transport, endosome to Golgi regulation of macroautophagy intracellular protein transport cellular response to interferon-gamma signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 112936 69091 Ensembl ENSG00000151502 ENSMUSG00000031988 UniProt Q4G0F5 Q8C0E2 RefSeq (mRNA) NM_052875 NM_178027 RefSeq (protein) NP_443107 NP_443107.1 NP_821170 Location (UCSC) Chr 11: 134.22 – 134.25 Mb Chr 9: 26.92 – 26.94 Mb PubMed search
Wikidata
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Further reading

• Haft CR, de la Luz Sierra M, Bafford R, Lesniak MA, Barr VA, Taylor SI (December 2000). "Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes". Mol. Biol. Cell. 11 (12): 4105–16. doi:10.1091/mbc.11.12.4105. PMC 15060. PMID 11102511.
• Kerr MC, Bennetts JS, Simpson F, Thomas EC, Flegg C, Gleeson PA, Wicking C, Teasdale RD (November 2005). "A novel mammalian retromer component, Vps26B". Traffic. 6 (11): 991–1001. doi:10.1111/j.1600-0854.2005.00328.x. PMID 16190980. S2CID 31954489.