Youjaes

Hi, my name is James Youlton. I'm primarily a computer scientist and mathematician. In 1992, I did some mathematical programming work for a scientist working on the Human Genome Project. Specifically, I wrote the "Titan Algorithm" to deconvolute the camera images of the band patterns on DNA test strips and properly separate out the peaks. The scientists were having a hard time with the math and the project was projected to take another 98 years to complete using the current method. If you have ever seen the raw test strips, they look like this:

The deconvoluted bands look like this:

The problem they were having was mathematically separating two bands that were close together and overlapping, as they appear as a "fat" peak, and sometimes a "bent" peak in the data. It took me about two weeks to solve their problem, as well as accelerate the analysis routine from 90 minutes per test to about a minute per test by optimizing the math computations. The scientist said my work would be used to "assembly line" the Human Genome Project, which happened, and the sequencing was completed only a few years later. The same method went on to to be used for other genomes, research, and diagnostic testing. I would like to write a wikipedia page describing the algorithm and how it works, which is relatively easy for another proficient programmer to verify. I will include sample graphs demonstrating the problem and the exact method for separating the bands using a convergent algorithm. If someone knows how to contact makers of DNA testing equipment to verify the claims about how it is done, that would be great. May I have permission to do so?

This is what history records about that event:

Youjaes (talk) 06:26, 13 March 2017 (UTC)