ANTISENSE RNA—ANITA

Is everything in the article relevant to the article topic? Is there anything that distracted you?

• I got lost reading the Discovery part. It just went over my head • Under “Function >> Histone Modification” and “Function >> Co-transcriptional regulation,” you go through a nice couple sentence introduction about what it is/how it works but with DNA methylation you jump into examples without explaining it as well

Is the article neutral? Are there any claims, or frames, that appear heavily biased toward a particular position?

• The article is neutral

Are there viewpoints that are overrepresented, or underrepresented?

• no

Check the citations. Do the links work? Does the source support the claims in the article?

• Citations 10 & 12 are not reviews but the rest all work and support the article

Is each fact supported by an appropriate, reliable reference? Where does the information come from? Are these neutral sources? If biased, is that bias noted?

• Definitely needs more citations, every fact should have a citation and there aren’t especially in “cotranscriptional regulation”, “therapeutic value” ,

Is any information out of date? Is anything missing that should be added?

• Not that I can think of