Abstract: The abstract was well written and informative, sticking to the guideline of a minimum of 300 words. Alternative names were listed, Neill-Dingwall syndrome. The key characteristics were also included and laid out in a logical fashion.
Signs and Symptoms: The physical signs and symptoms were described in great detail. As for the following symptoms listed in the abstract: failure to thrive, neurological disorders, photosensitivity, hearing loss, and cavities, there was no clear listing of these anywhere in this section.
Cause: The was no section listing the cause. I would recommend including this even if there is no known cause currently, and maybe just mentioning this for clarity.
Mechanism/Pathophysiology: Although the transcriptional mechanism was explained well on a molecular level, there was not a very clear connection to how this affects the physiology of the body. I would focus on including how this pathway alters the physiology, thus leading to the listed symptoms.
Diagnosis: The diagnosis process including available testing was listed and explained well. All of the various types of Cockayne syndrome were listed with quite detailed explanations of each.
--Bguillen1024 (talk) 23:57, 13 November 2019 (UTC)Brenda Guillen--Bguillen1024 (talk) 23:57, 13 November 2019 (UTC)
The abstract looks great and is well organized while also providing a brief overview of cockayne syndrome. The genetics section if also very well put together and also describes how DNA damage can not be repaired, as compared to an individual without this mutation, and leads to the signs and symptoms that are associated with this syndrome. I would suggest adding the "types" section into the signs and symptoms since these describe signs and symptoms pertaining to the type of syndrome. I also do not see anything about prognosis besides the brief statement of those diagnosised pass within the first or second decade. I recommend creating a section dedicated to prognosis and the lifespan according to each type. Here is a link that should help with this section https://rarediseases.info.nih.gov/diseases/6122/cockayne-syndrome. Overall the article is very detailed and informative. Aherrera09 (talk) 19:15, 15 November 2019 (UTC)aherrera09
- Where did you get this picture? Is it open access and free to use? Otherwise, you must remove it. If it is, give it an appropriate caption.
- If you have a header for cognitive and developmental, you need to include them here.
- Physical signs seem to be describing one child. Please generalize.
- Missing prognosis, epidemiology, recent research.