User talk:LittleWen/sandbox

Latest comment: 6 years ago by Mocarlo in topic Ming's peer review

Three wonderful things

1- The overall essay is well structured with three main sections

2- The sources you selected are excellent and more than three, great job!

3- I enjoyed reading the opening sentence of the third paragraph (charge selectivity). The topic is clearly laid out.

Three Areas of improvement

1- Some sentences are slightly confusing. For example, “mucus enables to absorb water to dehydrated through PH variations.” I would suggest spelling this section a little more clearly.

2- The first paragraph “Mucus enables to absorb…..mucus.” seems to be missing a citation. I would suggest adding one there.

3- Some minor mistakes. For example, the second paragraph, “this effect comprises” (should include of) “two steps.”

Great job overall 😊 Turks&Caicos (talk) 13:53, 29 November 2017 (UTC)Reply

Ming's peer review

edit

The following points should be clarified:

1. Please add Wiki links to the following items: swelling capacity, mucin, Polyelectrolyte, osmotic pressure, pKa.

2. Delete "Multiple polymers with charged molecules are called polyelectrolytes". Instead, add Wiki link to the first "polyelectrolyte" that appears in the article.

3. "Mucus enables to absorb water or dehydrated through pH variations" --> Mucus enables to absorb water or be dehydrated through pH variations.

4. "The charges of mucin are mainly provided by aspartic acids (pKa=3.9) and glutamic acids (pKa=4.2), so the number of charges in mucus is influenced by the pH value of solution." The change of charges is not inevitable if each aspartic acid and glutamic acid have the same number of charges. If different, please point it out.

5. "For example, the charge residue on mucin is protonated at a normal pH value of stomach, low approximately pH 2." I don't understand this sentence. Do you mean: For example, the charge residue on mucin is protonated in stomach because of low pH (≈2), which indicates little polyelectrolyte effect, resulting in compacted mucus with little swelling capacity.

The following points are just my personal feelings:

1. "The process of inducing this effect comprises two steps." --> Two steps are comprised to induce the process / To induce this effect, two steps are involved.

2. "When exposing in physiological ionic solution, the charged groups in the polyelectrolytes attract counter-ions with opposite charges, thereby leading to a solute concentration gradient." --> ... with opposite charges, leading to a solute concentration gradient. (the present participle, say, "leading" here, has incorporated the indication of "as a result" or "consequence of")

3. "An osmotic pressure is introduced to equalize the concentration of solute throughout the system by driving water to flow from the low concentration area to the high concentration area."

4. “The negative charges in mucus largely increase, thus inducing the polyeletrolyte effect and swelling of mucus. ” --> The negative charges in mucus increase significantly, inducing the polyeletrolyte effect and swelling of mucus.

5. Please modify the subtitle “Function of Mucus Adopting Tunable Swelling Capability”. I don't know how to improve it, but I believe it can be better: easier to understand, reflect the most important information of this paragraph.

6. "Among particles with various surface zeta potentials, cationic particles tend to have a low depth of penetration, neutral ones possess medium penetration, and anionic ones have largest penetration depth." --> Among particles with various surface zeta potentials, cationic, neutral and anionic particles tend to have a low, medium, and the largest depth of penetration, respectively.

Mocarlo (talk) 07:47, 30 November 2017 (UTC)Reply