Frederic E. Mohs | |
|---|---|
| Born | March 1, 1910 |
| Died | July 1, 2002 (aged 92) |
| Citizenship | United States |
| Alma mater | University of Wisconsin-Madison |
| Known for | Mohs surgery |
| Scientific career | |
| Fields | Medicine (dermatology) |
| Institutions | University of Wisconsin-Madison |
| Academic advisors | Michael F. Guyer |
12140Frederic Edward Mohs (March 1, 1910 – July 1, 2002) was a medical researcher and dermatologic surgeon who developed the Mohs micrographic surgery technique (commonly referred to as Mohs surgery) in 1936 as a research assistant at the University of Wisconsin–Madison.[1][2] Today, Mohs surgery is still recognized as the superior method for combating many types of high-risk skin cancers.[3]
Biography
editMohs was born in Burlington, Wisconsin. His father died when he was 3 months old, and the family moved to Madison, where his mother ran a boarding house. After initially considering a career as a radio engineer, he switched to medical studies in college. Mohs began developing his treatment in the 1930s, experimenting on rats, puppies, other animals. The breakthrough came when he discovered that applying a combination zinc chloride and bloodroot paste to malignant rat skin tissue allowed it to be removed surgically and examined under a microscope. He treated his first human patient on June 23, 1936. Mohs, who spent his working life at the University of Wisconsin, was a tireless advocate for the surgical procedure he had devised and taught it to doctors from all over the world.
In 1943 Mohs married Mary Ellen Reynolds, who died in 1995. Dr. Mohs died at his home in Madison, Wisconsin on July 2, 2002 at the age of 92.[4] He is survived by two sons, Frederic and Thomas, of Madison; and a daughter, Jane Shimming of Jupiter, Fla.
Mohs surgery
editMohs first tried to publish his findings and encouraged surgeons to learn the procedure. This was largely unsuccessful, as many surgeons were not comfortable learning skin pathology and laboratory techniques. Dermatologists, who are well trained in dermatopathology, and who treat skin cancers on a daily basis, quickly embraced the procedure. Today, most Mohs procedures are performed by dermatologists, although a small number of plastic surgeons, otolaryngologists, and pathologists are also practicing and using the procedure as well.
Mohs' technique was later modified by Perry Robins in the 1970s, using fresh-tissue frozen histology. Rather than using the anesthetic Mohs paste, local anesthetic is used. The fresh skin specimen is then mounted on a cryostat, and frozen sections are examined instead of the Mohs paste-fixed sections. This method is now commonly referred to as Mohs surgery, and occasionally chemosurgery, in reference to the Mohs paste Dr. Mohs initially used.
References
edit- ^ Lewis, Paul (5 July 2002). "Frederic Mohs, 92, Inventor Of Cancer Surgery Technique". The New York Times. New York City. Retrieved 2011-06-07.
- ^ Mohs, Frederic E. (2004), Snow, Stephen N.; Mikhail, George R. (eds.), Mohs Micrographic Surgery, Madison, WI: The University of Wisconsin Press, pp. 3–13
- ^ Rusciani, Luigi; Robins, Perry (2008). Textbook of Dermatologic Surgery. Vol. 2. Padova, Italy: Piccin Nuova Libraria S.p.A. pp. 669–675. ISBN 978-88-299-1898-0.
- ^ Obituary, The Wisconsin State Journal (Madison, WI), July 2, 2002
External Links
edit- "Origin and Process of Mohs Micrographic Surgery", by Frederic E. Mohs