Clinical data | |
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Pronunciation | oz en ox' a sin |
Trade names | Ozanex; Xepi |
AHFS/Drugs.com | Monograph |
MedlinePlus | a618010 |
License data |
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Routes of administration | Topical |
Drug class | Antibiotic (quinolone)[1] |
Legal status | |
Legal status | |
Identifiers | |
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Chemical and physical data | |
Formula | C21H21N3O3 |
Molar mass | 363.417 g·mol−1 |
3D model (JSmol) | |
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Ozenoxacin, sold under the brand names Ozanex and Xepi, is an antibiotic used to treat impetigo.[1] This includes impetigo due to methicillin-resistant S. aureus (MRSA).[3] It is applied to the skin as a cream.[3]
As little is absorbed through the skin; side effects are uncommon.[3] Side effects may include seborrheic dermatitis.[4] It is not expected to be harmful in pregnancy or breastfeeding.[1] It is a quinolone and works by blocking DNA gyrase A and topoisomerase IV.[1]
Ozenoxacin was approved for medical use in the United States and Canada in 2017.[1][5] In the United States a 30 gram tube of 1% cream costs about 340 USD as of 2021.[6] This amount in Canada costs about 53 CAD.[7]
References
edit- ^ a b c d e f "DailyMed - XEPI- ozenoxacin cream". dailymed.nlm.nih.gov. Archived from the original on 11 November 2021. Retrieved 10 November 2021.
- ^ "Xepi- ozenoxacin cream". DailyMed. 30 January 2020. Archived from the original on 17 October 2020. Retrieved 13 October 2020.
- ^ a b c d Robertson, Dirk B.; Maibach, Howard I. (2020). "61. Dermatologic pharmacology". In Katzung, Bertram G.; Trevor, Anthony J. (eds.). Basic and Clinical Pharmacology (15th ed.). New York: McGraw-Hill. p. 1112. ISBN 978-1-260-45231-0. Archived from the original on 2021-10-10. Retrieved 2021-11-07.
- ^ "Ozenoxacin Monograph for Professionals". Drugs.com. Archived from the original on 15 October 2020. Retrieved 10 November 2021.
- ^ Canada, Health (30 June 2017). "Notice: Prescription Drug List (PDL): Multiple Additions [2017-06-23]". www.canada.ca. Archived from the original on 8 July 2021. Retrieved 10 November 2021.
- ^ "Xepi Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 10 November 2021.
- ^ "Pharmacoeconomic Review Report" (PDF). CADTH. Archived (PDF) from the original on 19 October 2019. Retrieved 10 November 2021.