 | |
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized |
| Target | VEGF-A, angiopoietin 2[1] |
| Clinical data | |
| Trade names | Vabysmo |
| Other names | RO6867461; RG7716; faricimab-svoa |
| AHFS/Drugs.com | Monograph |
| License data | |
| Routes of administration | Intravitreal |
| Legal status | |
| Legal status | |
| Chemical and physical data | |
| Formula | C6506H9968N1724O1026S45 |
| Molar mass | 130197.05 g·mol−1 |
Faricimab, sold under the brand name Vabysmo, is a medication used to treat wet age-related macular degeneration (nAMD) and diabetic macular edema (DME).[1] It is given by injection into the eye.[1]
Common side effects include conjunctival bleeding.[1] Other side effects may include eye infection and allergic reactions.[1] Use is not recommended in pregnancy.[1] It is a monoclonal antibody, that blocks both vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang-2), thus decreasing new blood vessel growth in the eye.[1][5]
Faricimab was approved for medical use in the United States and Europe in 2022.[1][5] In the United Kingdom a 28.8 mg vial costs the NHS about £860.[6] In the United States 6 mg costs about 2,300 USD as of 2022.[7]
References
edit- ^ a b c d e f g h i j k l "Vabysmo- faricimab injection, solution". DailyMed. 7 February 2022. Archived from the original on 21 February 2022. Retrieved 20 February 2022.
- ^ "Archive copy". Archived from the original on 2022-10-13. Retrieved 2022-10-28.
{{cite web}}: CS1 maint: archived copy as title (link) - ^ "Summary Basis of Decision - Vabysmo". Health Canada. 31 August 2022. Archived from the original on 29 September 2022. Retrieved 29 September 2022.
- ^ "Vabysmo Product information". Health Canada. 25 April 2012. Archived from the original on 1 October 2022. Retrieved 30 September 2022.
- ^ a b c "Vabysmo EPAR". European Medicines Agency (EMA). 19 July 2022. Archived from the original on 14 October 2022. Retrieved 14 October 2022.
- ^ "Faricimab". SPS - Specialist Pharmacy Service. 16 November 2018. Archived from the original on 11 December 2022. Retrieved 11 December 2022.
- ^ "Vabysmo Prices, Coupons, Copay & Patient Assistance". Drugs.com. Retrieved 11 December 2022.