Clinical data | |
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Trade names | Winlevi |
Other names | CB-03-01; Breezula; 11-Deoxycortisol 17α-propionate; 17α-(Propionyloxy)- deoxycorticosterone; 21-Hydroxy-3,20-dioxopregn-4-en-17-yl propionate |
AHFS/Drugs.com | Monograph |
License data |
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Routes of administration | Topical (cream) |
Legal status | |
Legal status | |
Identifiers | |
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Chemical and physical data | |
Formula | C24H34O5 |
Molar mass | 402.531 g·mol−1 |
3D model (JSmol) | |
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Clascoterone, sold under the brand name Winlevi, is a medication used to treat acne in those who are at least 12 years old.[2] It is applied to the skin as a cream.[2]
Common side effects include redness, itchiness, dry skin, and localized swelling.[2] Other side effects may include high potassium.[2] Safety in pregnancy is unclear.[2] It is an androgen receptor inhibitor.[2] There appears to be minimal absorption into the circulation, when applied to skin.[3]
Clascoterone was approved for medical use in the United States in 2020.[2] It is not approved in either the United Kingdom or Europe as of 2022.[4] In the United States a 60 gram tube costs about 480 USD as of 2022.[5]
References
edit- ^ "Winlevi (clascoterone) cream, for topical use" (PDF). Cassiopea. Archived (PDF) from the original on 18 September 2020. Retrieved 9 September 2020.
- ^ a b c d e f g h i "DailyMed - WINLEVI- clascoterone cream". dailymed.nlm.nih.gov. Archived from the original on 28 October 2021. Retrieved 3 November 2022.
- ^ Kircik LH (July 2019). "What's new in the management of acne vulgaris". Cutis. 104 (1): 48–52. PMID 31487336. Archived from the original on 2020-10-26. Retrieved 2022-09-09.
- ^ "Clascoterone". SPS - Specialist Pharmacy Service. 3 March 2018. Archived from the original on 5 December 2021. Retrieved 3 November 2022.
- ^ "Winlevi". GoodRx. Archived from the original on 11 November 2022. Retrieved 3 November 2022.