User:Mr. Ibrahem/Butoconazole

Mr. Ibrahem/Butoconazole
Clinical data
Trade names	Gynazole-1, Femstat-3, others
AHFS/Drugs.com	Monograph
MedlinePlus	a682012
License data	US DailyMed: Butoconazole;
Pregnancy; category	AU: B3; ;
Routes of; administration	Vaginal cream
Drug class	Antifungal
Legal status
Legal status	US: OTC / Rx-only;
Identifiers
	IUPAC name (RS)-1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)sulfanylbutyl]imidazole;
Chemical and physical data
Formula	C19H17Cl3N2S
Molar mass	411.77 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc1ccc(cc1)CCC(Sc2c(Cl)cccc2Cl)Cn3ccnc3;
	InChI InChI=1S/C19H17Cl3N2S/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22/h1-5,7-8,10-11,13,16H,6,9,12H2 ; Key:SWLMUYACZKCSHZ-UHFFFAOYSA-N ;
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Butoconazole, sold under the brand name Gynazole-1 among others, is antifungal used to treat vaginal yeast infections.^[1] It is used inside the vagina.^[1]

Common side effects include burning, itchiness, and abdominal pain.^[1] Its use may weaken condoms in the 3 days following application.^[1] It may be used in pregnancy.^[1] It is an imidazole.^[1]

Butoconazole was first made in 1978 and approved for medical use in the United States in 1995.^[2]^[1] It is available over the counter.^[1] In the United States a dose costs about 105 USD as of 2022.^[3]

References

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k "Butoconazole Monograph for Professionals". Drugs.com. Archived from the original on 3 January 2022. Retrieved 12 January 2022.
^ Grayson, M. Lindsay; Crowe, Suzanne M.; McCarthy, James S.; Mills, John; Mouton, Johan W.; Norrby, S. Ragnar; Paterson, David L.; Pfaller, Michael A. (29 October 2010). Kucers' The Use of Antibiotics Sixth Edition: A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs. CRC Press. p. 1893. ISBN 978-1-4441-4752-0. Archived from the original on 12 January 2022. Retrieved 12 January 2022.
^ "Gynazole-1 Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 29 October 2016. Retrieved 12 January 2022.

[AHFS2022-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k "Butoconazole Monograph for Professionals". Drugs.com. Archived from the original on 3 January 2022. Retrieved 12 January 2022.

[2] Grayson, M. Lindsay; Crowe, Suzanne M.; McCarthy, James S.; Mills, John; Mouton, Johan W.; Norrby, S. Ragnar; Paterson, David L.; Pfaller, Michael A. (29 October 2010). Kucers' The Use of Antibiotics Sixth Edition: A Clinical Review of Antibacterial, Antifungal and Antiviral Drugs. CRC Press. p. 1893. ISBN 978-1-4441-4752-0. Archived from the original on 12 January 2022. Retrieved 12 January 2022.

[3] "Gynazole-1 Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 29 October 2016. Retrieved 12 January 2022.

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