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| Clinical data | |
|---|---|
| Trade names | Pepto-Bismol, Peptic Relief, Pink Bismuth, others |
| Other names | Bismuth salts |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a607040 |
| Routes of administration | By mouth |
| Legal status | |
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| Identifiers | |
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| Chemical and physical data | |
| Formula | C7H5BiO4 |
| Molar mass | 362.093 g·mol−1 |
| 3D model (JSmol) | |
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Bismuth subsalicylate, sold under the brand name Pepto-Bismol among others, is an medication used for diarrhea and heartburn.[1] Its use for heartburn; however, is not generally recommended in the United Kingdom.[2] It is also used along with other medications to treat Helicobacter pylori infection.[1][2] It is taken by mouth either as a liquid or a tablet.[1][2]
Common side effects include a black tongue or dark stool.[1] Severe side effects may include Reye's syndrome and neurological problems.[1] It should not be used in people who are allergic to aspirin and in large doses may result in salicylate poisoning.[1][2] Use is the last third of pregnancy may harm the baby.[1] It works by forming a protective coating inside the stomach.[3]
Bismuth subsalicylate came into medical use in the 1910s.[3] It is available as a generic medication and over the counter.[4] While it is often described as an "antacid", it does not have antacid properties.[4] In the United States 30 tabs of 262 mg costs about 11 USD.[5]
References edit
- ^ a b c d e f g "Bismuth Salts Monograph for Professionals". Drugs.com. Archived from the original on 28 March 2016. Retrieved 8 October 2020.
- ^ a b c d BNF 79 : March 2020. London: Royal Pharmaceutical Society. 2020. p. 73. ISBN 9780857113658.
- ^ a b Sneader, Walter (2005). Drug Discovery: A History. John Wiley & Sons. p. 59. ISBN 978-0-470-01552-0. Archived from the original on 2021-08-28. Retrieved 2020-10-09.
- ^ a b Brodin, Michael (1998). The Over-The-Counter Drug Book. Simon and Schuster. p. 48. ISBN 978-0-671-01380-6. Archived from the original on 2021-08-28. Retrieved 2020-10-09.
- ^ "Bismuth subsalicylate Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 19 January 2021. Retrieved 9 October 2020.