Clinical data | |
---|---|
Trade names | Stendra |
AHFS/Drugs.com | Monograph |
MedlinePlus | a614010 |
License data | |
Routes of administration | By mouth |
Drug class | PDE5 inhibitor[1] |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Onset of action | Within 15 min[2] |
Duration of action | 2 hr[2] |
Identifiers | |
| |
Chemical and physical data | |
Formula | C23H26ClN7O3 |
Molar mass | 483.96 g·mol−1 |
3D model (JSmol) | |
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Avanafil, sold under the brand names Stendra and Spedra, is medication used to treat erectile dysfunction.[1] It is taken by mouth.[3] Effects generally begin within 15 minutes and last for up to 2 hours.[2]
Common side effects include headache, flushing, stuffy nose, and back pain.[1] Other side effects may include priapism, vision loss, and hearing loss.[3] It should not be used with nitrovasodilator.[1] It should also be avoided in people with significant liver or kidney problems.[3] It is a PDE5 inhibitor and works by blocking the phosphodiesterase enzyme, thus increasing levels of cyclic guanosine monophosphate (cGMP).[1]
Avanafil was approved for medical use in the United States in 2012 and Europe in 2013.[3][1] In the United Kingdom 4 pills of 100 mg costs the NHS about £14 as of 2021.[4] This amount in the United States is about 210 USD.[5]
References
edit- ^ a b c d e f g h i "Spedra". Archived from the original on 11 April 2021. Retrieved 16 January 2022.
- ^ a b c d "Avanafil". American Society of Health-System Pharmacists. Archived from the original on 30 November 2020. Retrieved 16 January 2022.
- ^ a b c d "DailyMed - STENDRA- avanafil tablet". dailymed.nlm.nih.gov. Archived from the original on 17 April 2021. Retrieved 16 January 2022.
- ^ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 859. ISBN 978-0857114105.
- ^ "Stendra Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 15 October 2021. Retrieved 16 January 2022.