Listified from Category:American podcasters at 06:09, 20 October 2012 after it was mentioned on IRC that many of these may not be notable. The following is my quick review of each article and any comments on them.
- Adam Carolla - notable
- Adam Curry - notable
- Aisha Tyler - notable
- Alec Baldwin - notable
- Alex Lindsay - POV issues
- Amy Lamé - notable
- Andrew Koenig - notable
- Andy Ihnatko - POV issues
- Anji Bee - major linkspam, needs a revisit
- Bailey Jay - notable
- Baylen Leonard - AFD
- Ben Harvey - notable
- Ben Patrick Johnson - notable
- Benjamin Radford - notable
- Bob Torres - notable
- Bob Wood (author) - notable
- Brett Gelman - notable
- Brian Dunning (author) - notable
- Brian Ibbott - borderline notable. Will revisit in future.
- C.C. Chapman
- Cali Lewis
- Cara Carriveau
- Chemda Khalili
- Chris DiBona
- Chris Hardwick
- Chris Perrin
- D. J. Grothe
- Dan Benjamin
- Dan Carlin
- Dan Klass
- Dan McCoy
- Dave Rubin
- David Feldman (comedian)
- Declan McCullagh
- Denise Howell
- Derek Colanduno
- Doug Benson
- Dwight Schultz
- Eddie Pepitone
- Elliott Kalan
- Ethan Casey
- Evo Terra
- Feast of Fun
- Fiona Ritchie
- Frank Gruber (entrepreneur)
- George Hrab
- Graham Elwood
- Greg Fitzsimmons
- Greg Proops
- Heidi W. Durrow
- Howard Kremer
- Irene McGee
- Jackie Kashian
- Jake Kettle
- Janet Varney
- Jared Spool
- Jason Mantzoukas
- Jeff Tolle
- Jeffrey Dandurand
- Jenna Torres
- Jesse Thorn
- Jillian Michaels (personal trainer)
- Jimmy Dore
- Jimmy Pardo
- Joe Rogan
- John C. Dvorak
- John Dehlin
- John Edwards
- Jonah Ray
- Jonny McGovern
- Julie Klausner
- June Diane Raphael
- Justin Robert Young
- Kaiji Tang
- Katherine Lanpher
- Kathleen P. King
- Katie Morgan
- Keith Malley
- Kenneth Plume
- Kevin Smith
- Klaatu (podcaster)
- Kulap Vilaysack
- Kumail Nanjiani
- Kyle Hebert
- Larry Miller (entertainer)
- Lars Brownworth
- Leah D'Emilio
- Len Peralta
- Leo Laporte
- Madge Weinstein
- Marc Gunn
- Marc Maron
- Mark Jordan Legan
- Matt Besser
- Matt Mira
- Matt Walsh (comedian)
- Megan Morrone
- Merlin Mann
- Michael Butler (musician)
- Michael Zarnock
- Mick LaSalle
- Mignon Fogarty
- Mike Pesca
- Mike Watt
- Moira Gunn
- Molly Wood
- Moshe Kasher
- Mur Lafferty
- Natali Morris
- Neal Brennan
- Nikki Glaser
- Nilay Patel
- Norm Augustinus - notable, files may have copyright issues
- Pamela L. Gay
- Paul F. Tompkins
- Paul Gilmartin
- Paul Goebel
- Paul Levinson
- Paul Miller (American journalist)
- Paul Scheer
- Paul Tevis
- Paul Thurrott
- Penn Jillette
- Pete Holmes
- Piper Reese
- R. D. Reynolds
- Rafe Needleman
- Randy and Jason Sklar
- Rebecca Watson
- Regina Lynn
- Richard Bluestein
- Riki Lindhome
- Rob Paulsen
- Robert Kelly (comedian)
- Robert Scoble
- Robynn McCarthy
- Ross Payton
- Roy H. Williams (author)
- Sam Tripoli
- Sara Benincasa
- Sara Schaefer
- Scott Aukerman - notable, image tagged as needing source clarification on commons
- Scott Johnson (cartoonist)
- Scott Mosier
- Scott Sherman
- Scott Sigler
- Seth Morris
- Sharon Vaknin
- Stephen Euin Cobb
- Stephen J. Dubner
- Stephen Tobolowsky
- Steve Eley
- Steven Levitt
- Steven Novella
- Susie Bright
- Tariq Nasheed
- Tee Morris
- They Might Be Giants
- Thomas F. Wilson
- Tig Notaro
- Tim Farley
- Tim Henson
- Tim Street
- Todd Cochrane
- Todd Glass
- Tom Barbalet
- Tom Merritt
- Tom Vasel
- Tony Pittman
- Troy Rutter
- Veronica Belmont
- Violet Blue
- Wanda Wisdom
- William Eric Alexander - AFD
- Willie Brown (politician)