Dr. Sara Mahdavi is a scientist, author, speaker, and clinician [1].

File:Dr Sara Mahdavi.jpg

She holds the position of Research Fellow at the Harvard School of Public Health, Harvard University, in Boston, MA,[2] and serves as an adjunct professor at the University of Toronto, Canada. Dr. Mahdavi's studies genetics-environmental interactions to predict human health outcomes, with a special emphasis on precision medicine. Her focus is on customizing intervention approaches for individuals from diverse backgrounds to enhance the effectiveness and specificity of health interventions based on their DNA, rather than adopting a one-size-fits-all approach.

Dr Mahdavi is a speaker at medical conferences, government agencies, and popular media outlets Including On Doctors Radio with Host Dr Doris Day, MD CTV Toronto evening news [3] The Globe and Mail [4] Prevention Magazine [5] amongst others [6][7][8]. Her research interests and expertise revolve around incorporating precision medicine, precision nutrition, and personalized lifestyle approaches into clinical practice. The goal is to improve patient outcomes and reduce the risks of complications. She has authored over a dozen peer-reviewed journals, with many as the leading author. Some of her notable works include the differential association of coffee intake and kidney disease markers based on the genetic predictor of slow and fast metabolizers of caffeine [9] Magnitude of Differential association of prudent dietary patterns, [10] and in women with and without contraceptive use, and men [11] on fasting insulin and insulin sensitivity in a young cohort based on 9p21, one of the most common genetic predictors of cardiovascular disease, and Proteomic principal component analyses to understand the mechanism of genetic variation in 9p21 and it's relation to cardio metabolic disease [12] differences in contribution of dietary versus medication to changes in FGF23 and vitamin D status in dialysis patients [13], and modification in heart function and structure after patients start peritoneal dialysis treatment [14] amongst other publications [15]

Dr. Mahdavi's current research spans three distinct areas:

  1. Regenerative Medicine: This includes enhancing dermatology care, pre-operational care, surgical wound healing, and improving body composition.
  2. Reproductive Health: The focus is on enhancing male and female fertility, improving pregnancy success by better embryonic formation, and enhancing maternal-infant health.
  3. Diversity and Longevity Wellness: Investigating the best diets, fitness, and mindfulness approaches for diverse individuals based on their biology, culture, and psychology to unveil their secrets to healthy and happy living while preventing chronic diseases.

Overall, Dr. Sara Mahdavi's research endeavors aim to contribute significantly to advancing our understanding of personalized medicine and improving health outcomes across diverse populations.

References

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  1. ^ Mahdavi, Sara. "Dr Sara Mahdavi, PhD".
  2. ^ Mahdavi, Sara. "Academic Profiles". Harvard University.
  3. ^ Alberga, Hannah (2023). "Some coffee drinkers could face kidney dysfunction if they don't reduce caffeine, new U of T research finds". CTV News.
  4. ^ Beck, Leslie (2023). "More than three cups of coffee a day may harm kidney function in some people, study finds". The Globe and Mail.
  5. ^ Hasse, Madeline. "Drinking 3 Or More Cups of Coffee a Day May Increase Kidney Dysfunction Risk, Study Finds". Prevention Magazine.
  6. ^ Carro, Guillermina. "Cuánto café tomar al día como máximo si quieres cuidar tu salud". GQ Magazine.
  7. ^ Benz, Marie (2023). "COFFEE MAY RAISE RISK OF KIDNEY DISEASE AND HYPERTENSION IN ABOUT HALF OF POPULATION". Medical Research.
  8. ^ Common, David. "You may feel like you can't live without it... but new research says many of us can't handle a lot of coffee". Metro Morning News.
  9. ^ Mahdavi, Sara (2023). "CYP1A2 Genetic Variation, Coffee Intake, and Kidney Dysfunction". JAMA. PMID 36701157.
  10. ^ Mahdavi, Sara (2022). "Genetic variation in 9p21, dietary patterns, and insulin sensitivity". Frontiers in genetics. 13: 988873. PMID 36313440.
  11. ^ Mahdavi, Sara (2018). "Genetic variation in 9p21 is associated with fasting insulin in women but not men". PloS one. 13 (8): e0202365. doi:10.1371/journal.pone.0202365. PMID 30138332.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  12. ^ Mahdavi, Sara (2018). "Genetic Variation in 9p21 and the Plasma Proteome". Journal of proteome research. 17 (8): 2649–2656. PMID 29905076.
  13. ^ Mahdavi, Sara. "Associations of Calcium from Food Sources Versus Phosphate Binders with Serum Calcium and FGF23 in Hemodialysis Patients". Journal of Clinical Medicine. PMID 1615041.
  14. ^ Mahdavi, Sara. "Associations between echocardiographic findings and prospective changes in residual renal function in patients new to peritoneal dialysis". Nature Research, Scientific Reports. PMID 31804571.
  15. ^ National Institute of Health, National Library of Medicine. "Dr Sara Mahdavi". Pubmed. NIH.