Self containment by housing people in private rooms is important to prevent the spread of C. difficile between patients. C. difficile doesn’t often occur in people who are not taking antibiotics so it is important to not overuse antibiotics and to keep an eye on anyone who is using antibiotics. According to the CDC, "C. difficile has become the most common microbial cause of healthcare-associated infections in U.S. hospitals and costs up to $4.8 billion each year in excess health care costs for acute care facilities alone."