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Deoxycytidine kinase

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Nathanson DA, Armijo AL, Tom M, et al. Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication. The Journal of Experimental Medicine. 2014;211(3):473-486. doi:10.1084/jem.20131738.

(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949575/)

Hazra S, Szewczak A, Ort S, Konrad M, Lavie A. Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release. Biochemistry. 2011;50(14):2870-2880. doi:10.1021/bi2001032.

(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071448/)

C.L van der Wilt, J.R Kroep, W.J.P Loves, M.G Rots, C.J Van Groeningen, G.J Kaspers, G.J Peters, Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver, European Journal of Cancer, Volume 39, Issue 5, March 2003, Pages 691-697, ISSN 0959-8049, http://dx.doi.org/10.1016/S0959-8049(02)00813-4.

(http://www.sciencedirect.com/science/article/pii/S0959804902008134)

Keywords: Deoxycytidine kinase; Solid tumours; AML; Gemcitabine; Ara-C

Elias S.J. Arnér, Staffan Eriksson, Mammalian deoxyribonucleoside kinases, Pharmacology & Therapeutics, Volume 67, Issue 2, 1995, Pages 155-186, ISSN 0163-7258, http://dx.doi.org/10.1016/0163-7258(95)00015-9.

(http://www.sciencedirect.com/science/article/pii/0163725895000159)

Keywords: Deoxyribonucleoside metabolism; nucleoside analogues; deoxynucleoside kinases; nucleotidases; expression; substrate specificity

Yasukazu Yamada, Haruko Goto, Nobuaki Ogasawara, Purine nucleoside kinases in human T- and B-lymphoblasts, Biochimica et Biophysica Acta (BBA) - General Subjects, Volume 761, Issue 1, 1983, Pages 34-40, ISSN 0304-4165, http://dx.doi.org/10.1016/0304-4165(83)90359-8.

(http://www.sciencedirect.com/science/article/pii/0304416583903598)

Keywords: Purine nucleoside kinase; Adenosine kinase; Deoxyguanosine kinase; Deoxycytidine kinase; (Human lymphoblast)