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Comment: Please read the citation guides for details on properly citing articles. Urban Versis 32KB ⚡ (talk / contribs) 20:10, 29 September 2024 (UTC)
Alexandra Sotelo is an international neuroscientist specializing in consciousness studies, neurodegenerative diseases, and neuroaesthetics. She is recognized for her interdisciplinary approach, blending neurophilosophy with modern neuroscience to explore the mechanisms underlying conscious experience and well-being. Sotelo's work seeks to deepen the understanding of human cognition, particularly in the context of neurodegeneration and how the brain responds to art and aesthetics.
Research on Consciousness Sotelo’s primary focus is the neuroscience of consciousness, a complex and evolving field. She investigates how conscious awareness emerges from neural processes, studying the roles of various brain regions, including the basal ganglia and dopamine systems, in the initiation of voluntary movement and self-timed actions. Her research is significant in understanding how these processes are disrupted in neurodegenerative diseases such as Alzheimer’s.
A core theme of her work is examining how stimuli, such as art and sensory experiences, influence states of consciousness. Through her studies on neuroaesthetic phenomena like frisson—where art or music induces profound emotional responses—Sotelo investigates how these experiences contribute to emotional well-being and cognitive resilience. Her research has therapeutic implications, potentially enhancing mental health through tailored sensory experiences.
Neurodegeneration and Consciousness Sotelo’s work also bridges consciousness studies with neurodegenerative research, particularly focusing on how conditions like Alzheimer’s disease affect conscious awareness. Her published research investigates how neurodegenerative processes degrade the neural circuits responsible for memory, cognition, and the sense of self. By linking these insights to her broader work on consciousness, she aims to develop strategies to help preserve cognitive function in aging populations.
Publications and Contributions Sotelo, also known professionally as Alexis Sotelo, has published research in international peer-reviewed journals, including the Journal of Alzheimer’s Disease and The FASEB Journal. Notable works include:
Sotelo, A. (2023). The Prevention of Inflammation and the Maintenance of Iron and Hepcidin Homeostasis in the Gut, Liver, and Brain Pathologies. Journal of Alzheimer's Disease. DOI: 10.3233/jad-220224.
Kania, B., Sotelo, A., Ty, D., & Wisco, J. J. (2022). A Fight Against Gut Dysbiosis: Dendritic‐cell Derived Hepcidin and its Healing Role and Prevention of Neurologic Disease. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r6200.
Sotelo, A. (2022). A Qualitative Comparison of Manual and K‐means Segmentation for Whole‐slide Histology Images of Rabbit Vocal Folds. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r4314.
Sotelo, A. (2022). Gut Dysbiosis: A Review of the Effects of a High‐Fat Diet on Iron Regulation and Brain‐Derived Neurotrophic Factor (BDNF) Expression in the Brain‐Gut Axis. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r5664.
Sotelo, A. (2022). The Gut‐Brain Connection: The Inflammatory Role of IL‐6 Caused by a Western Diet. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r3514.
Ongoing Projects Sotelo continues to develop research at the intersection of consciousness and neurodegeneration, with a strong emphasis on the role of sensory and aesthetic experiences in enhancing cognitive resilience.
Membership and Service Sotelo is a member of the Royal Society of Medicine in London, GB.
References Sotelo, A. (2023). The Prevention of Inflammation and the Maintenance of Iron and Hepcidin Homeostasis in the Gut, Liver, and Brain Pathologies. Journal of Alzheimer's Disease. DOI: 10.3233/jad-220224.Journal of Alzheimer's Disease
Kania, B., Sotelo, A., Ty, D., & Wisco, J. J. (2022). A Fight Against Gut Dysbiosis: Dendritic‐cell Derived Hepcidin and its Healing Role and Prevention of Neurologic Disease. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r6200.FASEB Journal
Sotelo, A. (2022). A Qualitative Comparison of Manual and K‐means Segmentation for Whole‐slide Histology Images of Rabbit Vocal Folds. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r4314.FASEB Journal
Sotelo, A. (2022). Gut Dysbiosis: A Review of the Effects of a High‐Fat Diet on Iron Regulation and Brain‐Derived Neurotrophic Factor (BDNF) Expression in the Brain‐Gut Axis. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r5664. FASEB Journal
Sotelo, A. (2022). The Gut‐Brain Connection: The Inflammatory Role of IL‐6 Caused by a Western Diet. The FASEB Journal. DOI: 10.1096/fasebj.2022.36.s1.r3514.FASEB Journal