Sandbox for breast cancer
![]() | This is the sandbox page where you will draft your initial Wikipedia contribution.
If you're starting a new article, you can develop it here until it's ready to go live. If you're working on improvements to an existing article, copy only one section at a time of the article to this sandbox to work on, and be sure to use an edit summary linking to the article you copied from. Do not copy over the entire article. You can find additional instructions here. Remember to save your work regularly using the "Publish page" button. (It just means 'save'; it will still be in the sandbox.) You can add bold formatting to your additions to differentiate them from existing content. |
Article Draft
editPsychological Aspects and Supportive Care
editChemotherapy related cognitive impairment (CRCI) is another psychological aspect commonly associated with breast cancer patients, with about 10-40% of patients reporting symptoms. [1][2][3] Beginning in the late 1980's, evidence began to emerge that indicated problems with cognitive abilities such as executive functioning, verbal fluency, attention, and speed of processing for breast cancer patients after receiving chemotherapy. [4][5] Research points to the neurotoxicity of chemotherapy in causing these cognitive impairments, yet there has been occurrence of breast cancer patients reporting cognitive impairments before chemotherapy has even begun. [4][2][5] Factors such as age, menopausal status, depression, anxiety, fatigue, and distress may additionally contribute this "brain fog" rather than the chemotherapy. [4][2] Patients experiencing cognitive impairment may have difficulty with their careers, duties and usual routines, which may cause frustration and thus affect quality of life. [2][6] While impairment may last for some patients up to 10 years [1][7], fortunately most symptoms subside within four years. [3] Treatment wise, there are several proposed pharmaceutical options such as methylphenidate, erythropoietin and modafinil. [1][8][9]
In women with non-metastatic breast cancer, psychological interventions such as cognitive behavioral therapy can have positive effects on outcomes such as cognitive impairment, anxiety, depression and mood disturbance, and can also improve the quality of life. [10][11] Physical activity interventions as well as yoga and meditation may also have beneficial effects on health related quality of life, cognitive impairment, anxiety, fitness and physical activity in women with breast cancer following adjuvant therapy. [10][11][12]
References
edit- ^ a b c d Tannock, Ian F.; Ahles, Tim A.; Ganz, Patricia A.; van Dam, Frits S. (2004-06-01). "Cognitive Impairment Associated With Chemotherapy for Cancer: Report of a Workshop". Journal of Clinical Oncology. 22 (11): 2233–2239. doi:10.1200/JCO.2004.08.094. ISSN 0732-183X.
- ^ a b c d e Yang, Yesol; Hendrix, Cristina C (2018). "Cancer-Related Cognitive Impairment in Breast Cancer Patients: Influences of Psychological Variables". Asia-Pacific Journal of Oncology Nursing. 5 (3): 296–306. doi:10.4103/apjon.apjon_16_18.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ a b Matsuda, Tomohiro; Takayama, Tomoko; Tashiro, Manabu; Nakamura, Yu; Ohashi, Yasuo; Shimozuma, Kojiro (2005). "Mild cognitive impairment after adjuvant chemotherapy in breast cancer patients - evaluation of appropriate research design and methodology to measure symptoms". Breast Cancer. 12 (4): 279–287. doi:10.2325/jbcs.12.279. ISSN 1340-6868.
- ^ a b c d Hermelink, K. (2015-05-01). "Chemotherapy and Cognitive Function in Breast Cancer Patients: The So-Called Chemo Brain". JNCI Monographs. 2015 (51): 67–69. doi:10.1093/jncimonographs/lgv009. ISSN 1052-6773.
- ^ a b c Matsuda, Tomohiro; Takayama, Tomoko; Tashiro, Manabu; Nakamura, Yu; Ohashi, Yasuo; Shimozuma, Kojiro (2005). "Mild cognitive impairment after adjuvant chemotherapy in breast cancer patients - evaluation of appropriate research design and methodology to measure symptoms". Breast Cancer. 12 (4): 279–287. doi:10.2325/jbcs.12.279. ISSN 1340-6868.
- ^ a b Hutchinson, Amanda D.; Hosking, Jessica R.; Kichenadasse, Ganessan; Mattiske, Julie K.; Wilson, Carlene (2012). "Objective and subjective cognitive impairment following chemotherapy for cancer: A systematic review". Cancer Treatment Reviews. 38 (7): 926–934. doi:10.1016/j.ctrv.2012.05.002.
- ^ a b Silverman, Daniel H. S.; Dy, Christine J.; Castellon, Steven A.; Lai, Jasmine; Pio, Betty S.; Abraham, Laura; Waddell, Kari; Petersen, Laura; Phelps, Michael E.; Ganz, Patricia A. (2007). "Altered frontocortical, cerebellar, and basal ganglia activity in adjuvant-treated breast cancer survivors 5–10 years after chemotherapy". Breast Cancer Research and Treatment. 103 (3): 303–311. doi:10.1007/s10549-006-9380-z. ISSN 0167-6806.
- ^ a b Nelson, Christian J.; Nandy, Nina; Roth, Andrew J. (2007). "Chemotherapy and cognitive deficits: Mechanisms, findings, and potential interventions". Palliative and Supportive Care. 5 (3): 273–280. doi:10.1017/S1478951507000442. ISSN 1478-9515.
- ^ a b Pendergrass, J. Cara; Targum, Steven D.; Harrison, John E. (2018). "Cognitive Impairment Associated with Cancer". Innovations in Clinical Neuroscience. 15 (1–2): 36–44. ISSN 2158-8333. PMC 5819720. PMID 29497579.
- ^ a b c Lange, M.; Joly, F.; Vardy, J; Ahles, T.; Dubois, M.; Tron, L.; Winocur, G.; De Ruiter, M.B.; Castel, H. (2019). "Cancer-related cognitive impairment: an update on state of the art, detection, and management strategies in cancer survivors". Annals of Oncology. 30 (12): 1925–1940. doi:10.1093/annonc/mdz410. PMC 8109411. PMID 31617564.
{{cite journal}}
: CS1 maint: PMC format (link) - ^ a b c Janelsins, Michelle C.; Kesler, Shelli R.; Ahles, Tim A.; Morrow, Gary R. (2014). "Prevalence, mechanisms, and management of cancer-related cognitive impairment". International Review of Psychiatry. 26 (1): 102–113. doi:10.3109/09540261.2013.864260. ISSN 0954-0261. PMC 4084673. PMID 24716504.
{{cite journal}}
: CS1 maint: PMC format (link) - ^ a b Biegler, Kelly A.; Alejandro Chaoul, M.; Cohen, Lorenzo (2009). "Cancer, cognitive impairment, and meditation". Acta Oncologica. 48 (1): 18–26. doi:10.1080/02841860802415535. ISSN 0284-186X.