USS Lewis and Clark may refer to:
- USS Lewis and Clark (SSBN-644), a Benjamin Franklin-class ballistic missile submarine of the U.S. Navy
- USNS Lewis and Clark (T-AKE-1), a dry cargo ship of the U.S. Military Sealift Command
See also
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This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.