USS John Hancock may refer to:
- USS John Hancock (1850) was a steamship first authorized in 1850. She was sold in 1865.
- USS John Hancock (DD-981), was a Spruance-class destroyer, initiated in 1977 and retired in 2000.
See also
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This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.