USS James M. Gilliss may refer to one of the following United States Navy ships:
- USS James M. Gilliss (AMCU-13) (also AGS-13, AGSC-13, MHC-13), laid down as YMS-262; renamed 23 March 1945; struck and sold, 1960
- USNS James M. Gilliss (T-AGOR-4), an oceanographic research ship launched 1962; sold to Mexico as Altair (H-05) in 1996
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.