U16 may refer to:
Naval vessels
edit- German submarine U-16, various vessels
- HMS Amethyst (U16), a Black Swan-class sloop of the Royal Navy
- HMS Grimsby (U16), a Grimsby-class sloop of the Royal Navy
- SM U-16 (Austria-Hungary), a submarine of the Austro-Hungarian Navy
Other uses
edit- Bugatti U-16, an automobile engine
- Cubitruncated cuboctahedron
- Small nucleolar RNA SNORD16
- Uint16_t, an 16-bit unsigned integer
- Uppland Runic Inscription 16
- U16, or under-16, a type of basketball tournament by FIBA
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