Twitty is a surname. Notable people with the name include:
- Beth Holloway-Twitty (born c. 1961), American speech pathologist and motivational speaker
- Conway Twitty (1933–1993), American country music singer
- Howard Twitty (born 1949), American professional golfer
- Jasmine Twitty (born 1989), African-American municipal judge and youngest judge in American history
- Jeff Twitty (born 1957), American baseball player
- Michael W. Twitty (born 1977), African-American Jewish writer, culinary historian, and educator
- Panthea Twitty (1912–1977), American photographer, ceramist, and historian
- Pat Twitty, American songwriter who wrote an enduring jingle for Martha White flour in 1953
- Stephen Twitty (born 1963), United States Army Lieutenant General
- Victor C. Twitty (1901–1967), American biologist
Fictional characters
edit- Alan Twitty, a character in Even Stevens, an American TV series
- Eleanor Twitty, a character in the Ghostbusters universe