Tuisamoa or TuiSamoa is a surname. Notable people with the surname include:
- Agnes TuiSamoa (1932–2004), New Zealand activist
- Matthew Tuisamoa, Samoan rugby league player
- Tai Tuisamoa (born 1980), American rugby union player
Tuisamoa or TuiSamoa is a surname. Notable people with the surname include: