Tinyatoxin
Tinyatoxin (TTX or TTN) is a highly irritant analog of resiniferatoxin and capsaicin. It occurs naturally in Euphorbia poissonii.[1]
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3D model (JSmol)
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| ChemSpider | |
| ECHA InfoCard | 100.165.094 |
| MeSH | tinyatoxin |
PubChem CID
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| Properties | |
| C36H38O8 | |
| Molar mass | 598.69 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Tinyatoxin | |
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| Heat | Above peak |
| Scoville scale | 5,300,000,000 SHU |
It is a neurotoxin and (like its analogs) acts via vanilloid receptors of sensory nerves.[2] Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin but is still an ultrapotent analogue of capsaicin, with a heat intensity estimate of 300 to 350 times that of capsaicin.
ReferencesEdit
- ^ Euphorbia poissonii in BoDD – Botanical Dermatology Database
- ^ Szallasi, A. & Blumberg, P.M. (1991). "Characterization of vanilloid receptors in the dorsal horn of pig spinal cord". Brain Res. 547 (2): 335–338. doi:10.1016/0006-8993(91)90982-2. PMID 1884211.
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