Thomas Sykes may refer to:
- Thomas Sykes (academic) (died 1705), English academic
- Thomas Sykes (Mississippi politician) (fl. 1870s), American politician in Mississippi
- Thomas A. Sykes (c. 1835–?), American politician in North Carolina and Tennessee
- Thomas Hardcastle Sykes, English bleacher and businessman
This disambiguation page lists articles about people with the same name.
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