Chalers was the son and heir of the MP, Sir John Chalers. He married at some point before May 1407, a woman named Margaret. They had one son, Sir John Chalers, also an MP.
He was a Member (MP) of the Parliament of England for Cambridgeshire in 1417 and was selected High Sheriff of Cambridgeshire and Huntingdonshire for 1426–27.
- "CHALERS (DESCHALERS), Thomas (1383-1443), of Whaddon, Cambs. and Wyddial, Herts. | History of Parliament Online". www.historyofparliamentonline.org.