Thomas Appleby may refer to:
- Thomas Appleby (MP) (died 1413), MP for Southampton
- Thomas Appleby (composer) (c. 1488–1563), English Renaissance composer and church musician
- Thomas Appleby (bishop) (died 1395), Bishop of Carlisle
- T. Frank Appleby (1864–1924), U.S. Representative
This disambiguation page lists articles about people with the same name.
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