Template talk:Protein primary structure
Latest comment: 3 years ago by Kupirijo in topic Isodesmosine
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editSource Reference Quote:
Encyclopedia of Life Sciences Protein Structure: Unusual Covalent Bonds advanced Nancy L Scott, Pennsylvania State University, University Park, Pennsylvania, USA Juliette T J Lecomte, Pennsylvania State University, University Park, Pennsylvania, USA Copyright © 2005 John Wiley & Sons, Ltd. All rights reserved. DOI: 10.1038/npg.els.0003015 Article Online Posting Date: May 3, 2005
Table 1 The most common covalent modifications of amino acids in proteins
Amino acid Modification or product
- Arginine: N-methylation, N-glycosylation, glycation, ADP-ribosylation, deimination
- Asparagine: N-glycosylation, ADP-ribosylation, deamidation, isoaspartic acid formation, isopeptide bond crosslinks
- Aspartic acid: O-phosphorylation, O-methylation, isoaspartic acid formation
- Cysteine: S-methylation, S-alkylation, S-phosphorylation, ADP-ribosylation, S-nitrosylation, oxidation (disulfide bond, S-thiolation, sulfenic acid and higher oxidation state), prenylation, palmitoylation
- Glutamic acid: O-methylation, ADP-ribosylation, pyroglutamate formation, g-carboxylation
- Glutamine: N-methylation, ADP-ribosylation, deamidation, pyroglutamate formation, isopeptide bond crosslinks
- Glycine: Myristoylation (N-terminal), isopeptide bond formation
- Histidine: N-methylation, N-phosphorylation, nucleotidylation, diphthamide formation, collagen crosslinks
- Lysine: N-acylation, N-acetylation, N-methylation, deamination, imine formation, oxidation to aldehyde, hydroxylation, O-glycosylation, glycation, carbamylation, ubiquitination, sumoylation, collagen and other crosslinks
- Methionine: oxidation, formylation (N-terminal)
- Proline: Hydroxylation, O-glycosylation
- Serine: O-phosphorylation, O-acetylation, O-glycosylation, phosphoglycosylation, selenocysteine formationb
- Threonine: O-phosphorylation, O-glycosylation, nucleotidylation
- Tryptophan: C-mannosylation
- Tyrosine: O-phosphorylation, nucleotidylation, O-glycosylation, halogenation, nitration, sulfation, dityrosine linkage
- Amino terminus: N-methylation, N-acetylation, N-formylation, glycation, pyroglutamate formation (Gln or Glu), myristoylation (Gly), carbamylation
- Carboxy terminus: O-methylation, glypiation, amidation, ubiquitination, sumoylation
Isodesmosine
editShould isodesmosine be included (next to desmosine) as well? --kupirijo (talk) 13:07, 12 November 2020 (UTC)