| Pos | Team | Pld | W | L | PF | PA | PD | Pts | Qualification or relegation |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Olympiacos | 24 | 23 | 1 | 2223 | 1743 | +480 | 47 | Advanced to playoffs |
| 2 | Panathinaikos OPAP | 24 | 22 | 2 | 2003 | 1644 | +359 | 46 | |
| 3 | Kolossos H Hotels | 24 | 15 | 9 | 1801 | 1771 | +30 | 39 | |
| 4 | AEK Athens | 24 | 13 | 11 | 1827 | 1925 | −98 | 37 | |
| 5 | Promitheas Patras | 24 | 12 | 12 | 1857 | 1878 | −21 | 36 | |
| 6 | Larisa | 24 | 12 | 12 | 1856 | 1953 | −97 | 36 | |
| 7 | Aris Thessaloniki | 24 | 11 | 13 | 1832 | 1853 | −21 | 35 | |
| 8 | Peristeri bwin | 24 | 10 | 14 | 1808 | 1862 | −54 | 34 | |
| 9 | PAOK mateco | 24 | 10 | 14 | 1829 | 1818 | +11 | 34 | |
| 10 | Lavrio Megabolt | 24 | 8 | 16 | 1773 | 1928 | −155 | 32 | |
| 11 | Apollon Patras | 24 | 8 | 16 | 1748 | 1913 | −165 | 32 | |
| 12 | Ionikos | 24 | 6 | 18 | 1835 | 1988 | −153 | 30 | |
| 13 | Iraklis | 24 | 6 | 18 | 1795 | 1911 | −116 | 27[a] | Relegated to Greek A2 Basket League |
Updated to match(es) played on 14 May 2022. Source: ESAKE
Notes:
Notes: