Talk:Polyethylenimine

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Solubility issue: This page lists PEI as insoluble in acetone whereas a great many sources (including Sigma-Aldrich - http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=Product%20No.%7CBRAND_KEY&N4=21195-U%7CSUPELCO&N25=0&QS=ON&F=SPEC#test) list it as soluble in acetone. This needs to be resolved. —Preceding unsigned comment added by 64.127.10.254 (talk) 19:17, 5 January 2010 (UTC)

-> The insolubility refers to the linear PEI. Im working a lot with it a I can confirm that is insoluble in acetone and many other organic solvents. —Preceding unsigned comment added by 141.35.147.250 (talk) 07:39, 30 August 2010 (UTC)

This article issues that PEI has a strong toxicity and uses Vancha et al. 2004 as a reference. However there is no mention of toxicity in that particular article. In fact the article states that PEI is suitable and convenient as a coating reagent for several cell lines. I therefore suggest that the part dealing with toxicity of PEI should be removed. —Preceding unsigned comment added by 128.214.87.159 (talk) 14:00, 9 February 2010 (UTC)

Isn't this a misspelling of Polyethyleneimine? Jeff Knaggs (talk) 16:34, 9 February 2010 (UTC)

I'm making a lot of poly(ethylenimines) (note, this is the correct spelling) as part of my PhD. I'll rewrite parts. 67th Tigers (talk) 22:00, 2 April 2010 (UTC)

Sentence about solubility of PEI is misleading. PEI at low pH is soluble in hot and cold water since there is no free base at low pH.Dominik-jan (talk) 14:10, 2 October 2010 (UTC)

No, there is a comma separating the sub-clauses, hence it is correct.

The freebase of l-PEI is insoluble below 60-80oC in water, depending on molecular weight. Decreasing the pH to protonate the amine or increasing the ionic strength of solution (i.e. in a buffer system) will cause it to dissolve. As a hydrochloride salt it is already protonated and there is an entropic gain by solution. The main commercial supplier of l-PEI (polyPlus) supplies l-PEI as a hydrochloride salt in sterile water. 67th Tigers (talk) 18:17, 2 October 2010 (UTC)

Have you guys ever tried to dissolve LPEI in acid at a low pH (PH = 1-2)? Im synthesizing LPEIs for almost a year now and I can tell you it wont work. The LPEI hydrochloride is formed and it becomes insoluble. So LPEI is only soluble under slighly acidic conditions and at temperatures above the melting point. Furthermore, I can tell you that LEPI is insoluble in cholorform or acetone. —Preceding unsigned comment added by 141.35.40.136 (talk) 21:57, 7 October 2010 (UTC)

l-PEI is synthesised from the parent polymer (typically poly(2-ethyl-2-oxazoline)) at pH 1-2 (usually conc. HCl). l-PEI is soluble in acetone and chloroform, l-PEI.HCl salt (i.e. the raw product from hydrolysis) isn't. You don't work in the SAF? PS: If it's jetPEI then that is a poorly defined l-PEI.HCl salt and is considerably inferior to any reasonably synthesised l-PEI for most things. 67th Tigers (talk) 22:05, 8 October 2010 (UTC)

Polyimine?

Is this the same thing, related or different? Kortoso (talk) 18:50, 6 July 2016 (UTC)