Talk:P70-S6 Kinase 1

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Possible duplicate? edit

Latest comment: 9 years ago3 comments3 people in discussion

http://en.wikipedia.org/wiki/P70S6_kinase I'm afraid I don't know how to fix this however. Jazzvibes (talk) 05:37, 7 May 2012 (UTC)Reply

I think that that article is referring to the general protein, and this one is focussing more specifically on the human one and its gene. But this is a guess, it really needs attention from an expert. See also: Ribosomal s6 kinase, RPS6KA1 -Zynwyx (talk) 12:14, 20 May 2012 (UTC)Reply

Maybe need add information:
Selman C, Tullet JM, Wieser D. et al. (2009). Ribosomal protein S6 kinase 1 signaling regulates mammalian lifespan. Science; 326, 140 - 144; doi: http://dx.doi.org/10.1126/science.1177221
Pende M, Um SH, Mieulet V, et al., & Thomas G. (2004). S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol Cell Biol; 24, 3112 - 3124; doi: http://dx.doi.org/10.1128/MCB.24.8.3112-3124.2004
217.29.16.249 (talk) 13:12, 5 January 2015 (UTC)Reply

P70 edit

Latest comment: 9 years ago2 comments2 people in discussion

I thought the difference between P70s and P90s was P70s only have 1 catalytic domain? I'm unsure.

"This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein."

173.25.54.191 (talk) 16:54, 5 October 2013 (UTC)Reply

I think you are right. Uniprot has it annotated with just one kinase domain, clearly different from P90s. I'm going to remove that sentence.Wolma (talk) 17:01, 26 February 2015 (UTC)Reply

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