Talk:Drug nomenclature

Latest comment: 6 years ago by Therazzz in topic more sources and need for review

Addition of explanation behind certain suffixes edit

Would anyone else think it useful to add some explanations and diseases treated by the drugs when explaining the suffixes? Would this be too much for this article? An example would be -dipine drugs which is representative of DIhydroPyridINE Calcium channel blockers. Let me know what you think.Therazzz (talk) 16:02, 21 March 2018 (UTC)Reply

need inclusion of, and source for, the new cellular therapy "-cel" suffix edit

On August 30, 2017 the FDA approved tisagenlecleucel (Kymriah™) for B-cell precursor acute lymphoblastic leukemia (ALL). On October 18, 2017 the FDA approved axicabtagene ciloleucel (Yescarta™) for treatment of non-Hodgkins Lymphoma. These are instances of a type of gene therapy (called CAR-T) in which a patient's cells are removed, genetically engineered, and then readministered to the patient. Speedyboy (talk) 23:07, 19 October 2017 (UTC)Reply

A good point, but the since naming therapies is more scientifically ambiguous than simply naming small molecule drugs, it may oversimplify therapy and lead to inaccuracies. Therazzz (talk) 15:58, 21 March 2018 (UTC)Reply

more sources and need for review edit

This page needs more source and to be checked by some expert, especially the list. For example, loperaMIDE doesn't affect the kidney in contrast to what is said in this article. There are also a lot of mistakes (-azolam instead of azelam or -azepam) and repeated suffix (ex. cillin). Needs more expamples. Preceding unsigned comment added by 141.70.80.5 (talk) 16:36, 14 December 2013 (UTC)Reply

Agreed. This is a naive question but is this information well known in the related fields or is it a sub-specialty among doctors and pharmacists? It would seemed very specialized for chemists. What other fields cover this? Is this the type of information that is in the PDR? Some other book? Arbalest Mike (talk) 19:02, 16 October 2014 (UTC)Reply
Here's a good resource via the NIH: https://druginfo.nlm.nih.gov/drugportal/jsp/drugportal/DrugNameGenericStems.jsp Therazzz (talk) 16:05, 21 March 2018 (UTC)Reply

these suffixes need reviewing edit

I was trying to make a couple small tweaks when I realized that a LOT of these are incomplete, inaccurate, or flat out wrong, and they're pretty much all edits by the same user. I've removed them from the article and placed them here, I'm going to attempt to do some research and replace/correct them as time allows. I've already fixed a few, but if anyone else wants to chip in feel free. Kleptosquirrel (talk) 16:46, 31 December 2013 (UTC)Reply

-olol Beta 1 blocker Atenolol
-tidine H2 receptor antagonist Cimetidine, Ranitidine
-pine Ca2+ channel blocker Amlodipine, Nifedipine
-done Opioid analgesic Hydrocodone, Oxycodone, Methadone
-sone corticosteroid, anti-inflammatory Prednisolone, Prednisone
-nitrate vasodilator Isosorbide mononitrate, Isosorbide dinitrate
-conazole antifungal
-cillin antibacterial
-cyclin protein synthesis inhibitor
-navir protease inhibitor (HIV treatment) Indinavir, Nelfinavir, Atazanavir
-tryptan serotonin agonist (migrane treatmente) example
-ane inhaled anesthetics halothane
-cane local anesthetics lidocaine, cocaine
-azine anti-psychotic phenothiazine
-barbital anticonvulsant phenobarbital
-azelam benzodiazapines alprazolam
-zosin/-sin Alpha-1-Antagonists Silodosin, Doxazosin, Prazosin, Alfuzosin
-ipramine tricyclic antidepressant Imipramine
-etine SSRI antidepressants dapoxetine, fluoxetine, paroxetine, sertraline, zimelidine
-kinase/-place Thrombolytics Streptokinase, Urokinase, tPA (alteplase), anistreplase

Other drug suffixes not included above are: (-mine) anti-histamine (-pril) ACE I inhibitors, affects the kidney (-mide) loop diuretics (-lactone) potassium-sparing diuretics (-mol) bronchodilators, beta 2 adrenergic; for DOB (-pium) beta 2 adrenergic; for DOB, relaxes bronchi (-aluminum, magnesium, hydroxide) antacids (-zepam, -lam) anti-anxiety, major tranquilizers (caine) local anesthetics (-ide) oral hypoglycemics (-nium) neuromuscular blocking agent