Talk:DIAPH1

Merge proposal

This article is not only about the human protein diaphanous homolog 1 and the gene that encodes it (DIAPH1), but also orthologs in other species including mouse (MDia1). Furthermore, the {{PBB}} template that is transcluded into this article contains specific information about the orthologous mouse gene and protein. Finally this protein appears to share a very similar function in both mice and humans (regulation of actin polymerization). Hence it would make sense to merge these two articles into one. Boghog (talk) 18:05, 8 August 2010 (UTC)

My concern with merging any of the murine and human Diaph proteins is that currently very little is known of the human variants. For instance, there is limited data on Diaph2 and Diaph3. Plus the naming of these proteins is all over the place; eg. Why is mDia3 the equivalent to Diaph2 and why is mDia2 equivalent to Diaph3? Surely it cannot be related to function, as with the latter human proteins no one really knows what their phenotype is. Whilst mDia1 and Diaph1 are probably equivalent, I wouldn't merge any murine and human descriptors until we phenotypically characterize the human variants Diaph2 and Diaph3. — Preceding unsigned comment added by 149.171.20.143 (talk) 23:30, 28 May 2013 (UTC)