Talk:Citrate

Kidney stones

Could someone with a good knowledge of chemistry explain how citrates help prevent the formation of kidney stones? I imagine it would be because the large citrate ion does not form crystals when it bonds weakly to calcium etc, though my knowledge here is rather limited and I have no texts to refer to. This information would be very useful for people suffering from kidney stones, in terms of understanding how drinking say orange juice helps stop the formation of the stones (crystals). Richard001 06:15, 2 October 2006 (UTC)

Needs work

While this page is not a stub I feel it is not up to the usual wiki standard considering the central role of citrate in metabolism. It has affects on lipogenesis and is an allosteric affecter of many different enzymes and most likely loads of other things I'm not yet familiar with.--Drewlew 21:02, 9 September 2007 (UTC)

Expand

In addition to the above, some other topics needed: Dietary sources of citrate? Pharmaceutical sources? Therapies using citrate (eg for uric acid nephrolithiasis; see PMID 17531180)? --Una Smith (talk) 04:00, 24 October 2008 (UTC)

Yes I agree that this article needs much expanding, also please will someone add something about citrates anticoagulant properties and how citrate is added to blood taken for transfusion. The citrate binds the calcium ions (as citrate is a chelating agent) which prevents the blood from coagulating, thanks, 129.11.61.149 (talk) 22:43, 29 October 2008 (UTC)

Buffering

A contributor requests sources for the section on buffering. The relevant content was added by a multi-use IP (here) so no hope there. The section needs two sources, one for Maniatis (the "cookbook", I presume) and another for the corrected recipe. --Una Smith (talk) 21:46, 22 November 2008 (UTC)

Given [1] I suspect the original 'cookbook' is probably:

T. Maniatis, E.F. Fritsch and J. Sambrook, Molecular Cloning: A laboratory Manual, Cold Spring Harbor Laboratory, New York (1982).

but I don't currently have access to a library with a copy. Since what the OR suggests is pretty much what I'd expect a lab worker to do anyway, it can probably be removed. --Earin (t) 12:27, 25 November 2008 (UTC)

Redirect

I have transferred all relevant material thar was not already contained in citric acid to that article. Petergans (talk) 10:05, 7 December 2015 (UTC)

The redirect was reverted by user:66.87.31.79. Please do not revert again. This article is both redundant and inappropriate.

• It is redundant because all the relevant material is now contained in citric acid
• It is inappropriate because citrate and citric acid are two forms of the same substance, an acid and its conjugate base. I know of no other article in Wikipedia where an acid and its conjugate base are covered in separate articles. The redirect provides the correct mechanism so that users can find the information they are seeking, in the proper context. Petergans (talk) 10:49, 11 December 2015 (UTC)