Talk:Chlamydia pneumoniae
 | This  level-5 vital article is rated Start-class on Wikipedia's content assessment scale.It is of interest to the following WikiProjects: | ||||||||||
| |||||||||||
.jpg){kind=small}
Chlamydia taxonomy
editAccording to latest literature the "Chlamydophila" genus is not used any more, instead a single genus, Chlamydia, is now used, as well as nine species ( abortus, caviae, felis, muridarum, pecorum, pneumoniae, psittaci, suis and trachomatis). http://femspd.oxfordjournals.org/content/67/2/89.full Could someone update this article as well as all the other Chlamydia articles?
- After reading your cited article, "In Chlamydia veritas," I think you have a good point. Personally, I don't intend to attempt such an extensive editing project involving a number of articles, however.--71.36.127.39 (talk) 19:48, 29 September 2016 (UTC)
2018 Taxonomic Status
editThe split of the genus into Chlamydia and Chlamydophila was based on a single gene, 16S rRNA. Subsequent complete genome sequencing showed that Chlamydophila and Chlamydia are not a monophyletic genera, and it is proposed that the original genus Chlamydia be restored.
"The previous taxonomic separation of the genus based on ribosomal sequences is neither consistent with the natural history of the organism revealed by genome comparisons, nor widely used by the Chlamydia research community 8 years after its introduction; thus, it is proposed to reunite the Chlamydiaceae into a single genus, Chlamydia."[1]
"Glossary. Chlamydiaceae: a family of obligate intracellular bacteria that once included two genera, Chlamydia and Chlamydophila, but has since been revised to the single genus Chlamydia"[2]
"We conclude that neither generally used 16S rRNA sequence identity cut-off values nor parameters based on genomic similarity consistently separate the two genera. Notably, no easily recognizable phenotype such as host preference or tissue tropism is available that would support a subdivision. In addition, the genus Chlamydophila is currently not well accepted and not used by a majority of research groups in the field. Therefore, we propose the classification of all currently recognized Chlamydiaceae species in a single genus, the genus Chlamydia."[3] --Canavalia 00:55, 11 December 2018 (UTC)
References
- ^ Stephens, R.S., Myers, G., Eppinger, M. and Bavoil, P.M., 2009. Divergence without difference: phylogenetics and taxonomy of Chlamydia resolved. FEMS Immunology & Medical Microbiology, 55(2), pp.115-119.
- ^ Bachmann, N.L., Polkinghorne, A. and Timms, P., 2014. Chlamydia genomics: providing novel insights into chlamydial biology. Trends in Microbiology, 22(8), pp.464-472.
- ^ Sachse, K., Bavoil, P.M., Kaltenboeck, B., Stephens, R.S., Kuo, C.C., Rosselló-Móra, R. and Horn, M., 2015. Emendation of the family Chlamydiaceae: proposal of a single genus, Chlamydia, to include all currently recognized species. Systematic and applied microbiology, 38(2), pp.99-103.
C. trachomatis
editThe following line (in Symptoms and diagnosis) is of dubious veracity at best:
"Most patients with Chlamydia pneumoniae may not test positive for C. trachomatis since the bacteria is localized in the lungs but may infect a non infected partner through oral sex in which case the partner will develop Chlamydia Trachomatis."
Unless I completely misunderstand this, it is not accurate. If there is someone more informed about Chlamydial infections who would like to tackle this, please go ahead. Otherwise, I'll be back in a few days to take a shot.206.190.137.34 (talk) 19:23, 21 May 2008 (UTC)
- It's difficult to avoid confusing these two different species of Chlamydia. But doing so is like comparing apples to oranges. They're not the same. Although many different species of pathogenic Chlamydia have been identified thus far, more shall probably be discovered in the near future. Dr. B. R. Lang (talk) 13:54, 5 August 2008 (UTC)
C. pneumoniae linked to MI (Myocardial Infarction)?
edit"Unfortunately, as of 2005, no treatment of infection has not been shown to decrease incidence of myocardial infarction."
...what? 128.255.95.132 22:42, 21 January 2006 (UTC)
- Fixed, thanks InvictaHOG 03:55, 22 January 2006 (UTC)
Jan 18th, 07: added reference for role in atherosclerosis (Blasi et al). I am no expert here, but there is no mention in the article about 'chlamydia pneumoniae persistence'which has implications for its treatment.--Michele F 09:01, 28 January 2007 (UTC)
Controversial?
edit"It may also be contained within heat-resistant fibers currently being injected into the atmosphere by a covert world-wide aerosol-disseminating program through modified high-altitude unmarked jet aircraft." Reference: http://www.carnicom.com/morgobs6.htm
Is this a reliable source? Is this a mainstream opinion? I think it should be revised, and not just called "a minor edit". --Asuka Rei (talk) 22:44, 18 May 2008 (UTC)
- The short answer is, No. I've heard somewhere that elephants can fly, but I think that was a Walt Disney cartoon. Dr. B. R. Lang (talk) 13:06, 5 August 2008 (UTC)
"The first known case of infection with C. pneumoniae was a case of sinusitis in Taiwan." As far as I know, this is an incorrect statement. The original TWAR organism was isolated from the eye of a subject with trachoma in Taiwan, found to be an "atypical" C. trachomatis (stained with starch - more like C. psittaci) and stored in a freezer in Seattle for decades until Dr. Pekka Saikku, under the guidance of Dr. J. T. Grayston, prepared antibodies to TWAR and proved that this previously unknown Chlamydia was responsible for an outbreak of community acquired pneumonia in Finland.----DL Hahn
Extend this article?
editAs a reader of Wikipedia, I find it weird that Chlamydophila pneumoniae article is so brief. I think it is very discussed topic and one that interests doctors, patients etc.
I have stumbled upon a page "Chlamidia pneumonia Help and Treatment" with many information, unfortunately being a layman, I cannot evaluate validity of those information.
Are there any other valid sources? Is there anyone who could complete this article? — Preceding unsigned comment added by 89.176.217.174 (talk) 14:00, 11 January 2012 (UTC)
Extend this article? Sure, extend it !
editYou are right, its missing lot of information, Chlamydia have 3 living forms, aberrant body is missing here. The world population is already infected so now its late to do anything. Penicillin and other inducors is causing the 3th form, aberrant body and as its underdiagnosed and not cured we cants stop it anymore. Good source for information is NCBI. Lot of diseases is just the manifestation of chlamydia, example is multiple sclerosis, sarcoidosis, morbus conn, anemia of chronic disease ( ACD ), Alzheimer ( together with Herpes Virus ) etc.. I am hard on study all this, based on my public NCBI List: http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/49876291/. --Abrahadabrah (talk) 14:56, 29 March 2016 (UTC)
Thyroid gland
edit"Infection also causes the thyroid gland to reduce production of the 5’deiodinase enzyme that is necessary to make the conversion of the less active T4 hormone to the more effective and metabolically active T3 hormone. The T3 hormone regulates more than 300 functions of the body. Most thyroid tests will display normal results even after the thyroid has been affected. Usually a Reverse-T3 test will show an abnormality. A T3 shortage will results in sub-clinical Hypothyroidism [TSH 2.5 to 5.5] or Hypothyroidism, both of which will gradually cause symptoms such as excess uric acid, coronary artery disease, cardiac tamponade, elevated cholesterol, tinnitus, elevated antibodies and triggering of HSP60 proteins as well as chronic shortages of micro-nutrients such as potassium, magnesium, zinc, and almost all vitamins. The Hypothyroidism eventually causes Hypogonadism, i.e lower levels of Testosterone in the body. This in turn will develop into prostatitis i.e an enlargement of the Prostate."
The above contains no citations, and sounds pretty dubious to me. I am going to remove that text because it, at best, stretches the truth out of all proportion.--71.36.127.39 (talk) 19:20, 29 September 2016 (UTC)