Talk:Bioorthogonal chemistry

Latest comment: 8 years ago by 84.113.127.57 in topic SPAAC raction rates

SPAAC raction rates edit

Where are those taken from? They are missing temperature and solvent (which can change the rate of cycloadditions quite a bit). 84.113.127.57 (talk) 21:29, 7 March 2016 (UTC)Reply


Staudinger Ligation Mechanism error edit

The image you have for the Staudinger ligation (i.e. this: http://en.wikipedia.org/wiki/File:Staudingerligmech.png) has a small error. The issue is that it is shown as regenerating the phosphine in the end of the reaction. This is not the case, a phosphine oxide is generated by this process (amazing things could be done if water could reduce phosphorous V into phosphorous III). Just take the final species and make sure there is a P=O at the end, then I believe you are all good.149.155.222.31 (talk) 17:12, 18 October 2013 (UTC)Reply

-Wait Scratch that being all, also the transition state in the brackets [] has a phenyl ring integrated into the phosphorous-nitrogen heterocycle. That "Ph" in the ring should be another "N". I'd say that is it, but if I do, then I might find another error five seconds later like last time.149.155.222.31 (talk) 17:17, 18 October 2013 (UTC)Reply