Talk:Aconitase

Fluoroacetate and fluorocitrate

There should be mention made of the effects of theses toxic fluorides on aconitase. 134.250.31.124 18:29, 23 February 2007 (UTC)

There now is mention in the 'Function' section, but it says "Fluoroacetate, in the citric acid cycle, can innocently enter as fluorocitrate. However, aconitase cannot bind this substrate and thus the citric acid cycle is halted." In contrast, the page on Sodium fluoroacetate says "Fluorocitrate binds very tightly to aconitase, thereby halting the citric acid cycle", which seems more likely as an explanation. Tslumley (talk) 07:29, 8 April 2023 (UTC)

Isocitrate diagram

The carboxylic acid is deprotonated in isocitric acid and the diagram incorrectly shows it protonated. Also, why does the first diagram show citric acid, when the molecule in the reaction is citrate? —Preceding unsigned comment added by 84.65.120.20 (talk) 09:39, August 28, 2007 (UTC)

fluoroacetate

The enzyme is not blocked by fluoroacetate but by fluorocitrate!--Stone (talk) 08:21, 9 February 2011 (UTC)

Mechanism

The enzyme mechanism is incorrect, the first step doesn't make any sense and is not proposed by either of the references. 198.109.220.2 (talk) 15:07, 21 January 2014 (UTC)

Still not correct. Hichris (talk) 15:59, 27 January 2016 (UTC)

External links modified

Hello fellow Wikipedians,

I have just modified one external link on Aconitase. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

• Added archive https://web.archive.org/web/20120324072437/http://web.ku.edu/~crystal/taksnotes/Biol_638/notes/chp_16.pdf to http://web.ku.edu/~crystal/taksnotes/Biol_638/notes/chp_16.pdf

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 03:27, 26 June 2017 (UTC)