Testis-specific Y-encoded protein 1 is a protein that in humans is encoded by the TSPY1 gene.[3]

TSPY1
Identifiers
AliasesTSPY1, CT78, DYS14, TSPY, pJA923, testis specific protein, Y-linked 1, testis specific protein Y-linked 1
External IDsOMIM: 480100; HomoloGene: 87844; GeneCards: TSPY1; OMA:TSPY1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003308
NM_001197242
NM_001320964

n/a

RefSeq (protein)

NP_001184171
NP_001307893
NP_003299

n/a

Location (UCSC)Chr Y: 9.47 – 9.47 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Approximately 35 copies of this gene are present in humans, but only a single, nonfunctional orthologous gene is found in mice. Two transcript variants encoding different isoforms have been found for this gene.[4] The protein is strongly overexpressed in gonadoblastoma.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000258992Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: TSPY1 Testis specific protein, Y-linked 1".
  4. ^ "TSPY1 testis specific protein Y-linked 1 [Homo sapiens (human)] - Gene - NCBI".
  5. ^ Schnieders F, Dörk T, Arnemann J, et al. (1997). "Testis-specific protein, Y-encoded (TSPY) expression in testicular tissues". Hum. Mol. Genet. 5 (11): 1801–7. doi:10.1093/hmg/5.11.1801. PMID 8923009.

Further reading

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