In molecular biology, P73 antisense RNA 1T (non-protein coding), also known as TP73-AS1 or PDAM, is a long non-coding RNA. It may regulate apoptosis via regulation of p53-dependent anti-apoptotic genes. It may play a role in the development of oligodendroglial tumours.[1]
References
edit- ^ Pang JC, Li KK, Lau KM, Ng YL, Wong J, Chung NY, Li HM, Chui YL, Lui VW, Chen ZP, Chan DT, Poon WS, Wang Y, Mao Y, Zhou L, Ng HK (November 2010). "KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells". Brain Pathology. 20 (6): 1021–1032. doi:10.1111/j.1750-3639.2010.00405.x. PMC 8094719. PMID 20477830.
Further reading
edit- Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (October 1997). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Research. 4 (5): 345–349. doi:10.1093/dnares/4.5.345. PMID 9455484.
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