Thymosin beta-10 is a protein that in humans is encoded by the TMSB10 gene.[3][4][5] TMSB10 is a member of the beta-thymosin family of peptides.

TMSB10
Identifiers
AliasesTMSB10, MIG12, TB10, thymosin beta 10
External IDsOMIM: 188399; GeneCards: TMSB10; OMA:TMSB10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021103

n/a

RefSeq (protein)

NP_066926

n/a

Location (UCSC)Chr 2: 84.91 – 84.91 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

TMSB10 plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).[citation needed]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000034510Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ McCreary V, Kartha S, Bell GI, Toback FG (Jun 1988). "Sequence of a human kidney cDNA clone encoding thymosin beta 10". Biochem Biophys Res Commun. 152 (2): 862–6. doi:10.1016/S0006-291X(88)80118-9. PMID 3365256.
  4. ^ Santelli G, Califano D, Chiappetta G, Vento MT, Bartoli PC, Zullo F, Trapasso F, Viglietto G, Fusco A (Oct 1999). "Thymosin beta-10 gene overexpression is a general event in human carcinogenesis". Am J Pathol. 155 (3): 799–804. doi:10.1016/s0002-9440(10)65178-4. PMC 1866886. PMID 10487837.
  5. ^ "Entrez Gene: TMSB10 thymosin, beta 10".

Further reading

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