TB10Cs5H2 is a member of the H/ACA-like class of non-coding RNA (ncRNA) molecule that guide the sites of modification of uridines to pseudouridines of substrate RNAs. It is known as a small nucleolar RNA (snoRNA) thus named because of its cellular localization in the nucleolus of the eukaryotic cell. TB10Cs5H2 is predicted to guide the pseudouridylation of SSU ribosomal RNA (rRNA) at residue Ψ131.[1]

Consensus structure of TB10Cs5H2

References

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  1. ^ Myslyuk I, Doniger T, Horesh Y, Hury A, Hoffer R, Ziporen Y, Michaeli S, Unger R (November 5, 2008). "Psiscan: a computational approach to identify H/ACA-like and AGA-like non-coding RNA in trypanosomatid genomes". BMC Bioinformatics. 9: 471. doi:10.1186/1471-2105-9-471. PMC 2613932. PMID 18986541.