Staphylococcus virus G1 is a virus of the family Herelleviridae, genus Kayvirus.[1][2]
| Staphylococcus virus G1 | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Duplodnaviria |
| Kingdom: | Heunggongvirae |
| Phylum: | Uroviricota |
| Class: | Caudoviricetes |
| Order: | Caudovirales |
| Family: | Herelleviridae |
| Genus: | Kayvirus |
| Species: | Staphylococcus virus G1
|
As a member of the group I of the Baltimore classification, Staphylococcus virus G1 is a dsDNA virus. All the family Herelleviridae members share a nonenveloped morphology consisting of a head and a tail separated by a neck. Its genome is linear. The propagation of the virions includes the attaching to a host cell (a bacterium, as Staphylococcus virus G1 is a bacteriophage) and the injection of the double stranded DNA; the host transcribes and translates it to manufacture new particles. To replicate its genetic content requires host cell DNA polymerases and, hence, the process is highly dependent on the cell cycle.[3]
The Gp67 protein of G1 has been found to interact with its host's RNA polymerase though an interaction with a sigma factor.[4][5]
The phage contains a genome of 138,715 base pairs with a 30.4% of GC content and 214 predicted genes; this means that the 88.5% of the DNA is coding open reading frames, and therefore the gene density (the number of genes per kilobase) is 1.54.[6]
References edit
- ^ "Virus Taxonomy: 2019 Release". talk.ictvonline.org. International Committee on Taxonomy of Viruses. Retrieved 6 May 2020.
- ^ Adams, MJ; Carstens, EB (2012). "Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2012)". Archives of Virology. 157 (7): 1411–22. doi:10.1007/s00705-012-1299-6. PMC 7086667. PMID 22481600.
- ^ Baltimore, D (1971). "Expression of animal virus genomes". Bacteriological Reviews. 35 (3): 235–41. doi:10.1128/br.35.3.235-241.1971. PMC 378387. PMID 4329869.
- ^ Osmundson, J; Darst, SA (1 January 2013). "Biochemical insights into the function of phage G1 gp67 in Staphylococcus aureus". Bacteriophage. 3 (1): e24767. doi:10.4161/bact.24767. PMC 3694059. PMID 23819108.
- ^ Dehbi, M.; Moeck, G.; Arhin, F. F.; Bauda, P.; Bergeron, D.; Kwan, T.; Liu, J.; McCarty, J.; DuBow, M.; Pelletier, J. (17 April 2009). "Inhibition of Transcription in Staphylococcus aureus by a Primary Sigma Factor-Binding Polypeptide from Phage G1". Journal of Bacteriology. 191 (12): 3763–3771. doi:10.1128/JB.00241-09. PMC 2698411. PMID 19376864.
- ^ Kwan, T; Liu, J; Dubow, M; Gros, P; Pelletier, J (2005). "The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages". Proceedings of the National Academy of Sciences of the United States of America. 102 (14): 5174–9. Bibcode:2005PNAS..102.5174K. doi:10.1073/pnas.0501140102. PMC 556006. PMID 15788529.
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