Spiral waves are travelling waves that rotate outward from a center in a spiral. They are a feature of many excitable media. Spiral waves have been observed in various biological systems[1][2] including systems such as heart ventricular fibrillation,[3] retinal spreading depression,[4] Xenopus oocyte calcium waves,[5] and glial calcium waves in cortical tissue culture.[6]

Spiral Wave Dynamics in a Mathematical Model of Human Ventricular Tissue


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  2. ^ Murray JD. (2003). Mathematical Biology II: Spatial models and biomedical applications. New York: Springer-Verlag.
  3. ^ Davidenko JM, Pertsov AV, Salomonsz R, Baxter W, Jalife J (1992). "Stationary and drifting spiral waves of excitation in isolated cardiac muscle". Nature. 355: 349–351. doi:10.1038/355349a0. PMID 1731248.
  4. ^ Gorelova NA, Bures J (1983). "Spiral waves of spreading depression in the isolated chicken retina". J Neurobiol. 14: 353–363. doi:10.1002/neu.480140503. PMID 6619832.
  5. ^ Lechleiter J, Girard S, Peralta E, Clapham D (1991). "Spiral calcium wave propagation and annihilation in Xenopus laevis oocytes". Science. 252: 123–126. doi:10.1126/science.2011747. PMID 2011747.
  6. ^ Verkhratsky A, Orkand RK, Kettenmann H (1998). "Glial calcium: homeostasis and signaling function". Physiol. Rev. 78: 99–141. doi:10.1152/physrev.1998.78.1.99. PMID 9457170.