Look up spighi in Wiktionary, the free dictionary.
Spighi is an Italian surname. Notable people with the surname include:
- Cesare Spighi (1854–1929), Italian engineer and architect
- Francesco Spighi (18th century), Florentine artisan
- Garibaldi Spighi (1891–1978), Italian horse rider
- Mirco Spighi (born 1990), Italian football player